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Explore A-Z conditions
Endometriosis
Cannabis for Endometriosis
50% of those with endometriosis suffer from chronic pain, and 70% of those with endometriosis suffer from pain during menstruation, called dysmenorrhea. Around 25% of women with endometriosis have no symptoms at all. Endometriosis affects an estimated 10.8 million people globally, as of 2015. The uterus contains the reproductive system’s highest concentration of the endocannabinoid anandamide (AEA). Anandamide is analogous to THC, and taking THC may increase estrogen production, and cannabidiol (CBD) may bind to estrogen receptors. Cannabinoids may be useful in treating the chronic pain and anxiety associated with endometriosis.
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Animal Study
3
Clinical Trial
1
Laboratory Study
1
Meta-analysis
11
Total studies
Endometriosis
16
Positive
13 studies
81%
Inconclusive
3 studies
19%
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Relevant studies
The information in our comprehensive A to Z encyclopedia comes from real scientific studies.
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- Antiproliferative Effects of Cannabinoid Agonists on Deep Infiltrating Endometriosis.
- Cannabidiol for the Management of Endometriosis and Chronic Pelvic Pain
- Cannabidiol Use, Substitution for Medications, and Perceptions of Effectiveness in Women with Chronic Pelvic Pain
- Cannabis Use for Endometriosis: Clinical and Legal Challenges in Australia and New Zealand
- Effect of palmitoylethanolamide-polydatin combination on chronic pelvic pain associated with endometriosis: preliminary observations