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Explore A-Z conditions
Neuroblastoma
Cannabis for Neuroblastoma
Neuroblastoma is a rare type of cancer that typically affects babies and young children. There are around 700 to 800 new cases of neuroblastoma every year in the US.
Neuroblastomas usually occur in one of the adrenal glands situated above the kidneys, or in nerve tissue running alongside the spinal cord in the neck, chest, stomach or pelvis. Neuroblastoma can spread to other organs, such as bone marrow, lymph nodes, liver and skin. Symptoms include fatigue, pale skin, bone pain, bluish lumps on the skin, bruising around the eyes, breathing problems and difficulty swallowing, a swollen and painful stomach, constipation, and difficulties walking.
One study has shown that both THC and CBD displayed anti-cancer activity in neuroblastoma cells in culture and in animals. More evidence is needed to prove cannabinoids’ efficacy in humans, but the results are promising.
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Animal Study
2
Clinical Meta-analysis
1
Laboratory Study
29
Meta-analysis
7
Total studies
Neuroblastoma
39
Inconclusive
27 studies
69%
Positive
11 studies
28%
Negative
1 studies
3%
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Relevant studies
The information in our comprehensive A to Z encyclopedia comes from real scientific studies.
Uncover the detailed results of these studies and find out how effective medical marijuana is for dozens of conditions.
- 2-Arachidonoylglycerol, a putative endogenous cannabinoid receptor ligand, induces rapid, transient elevation of intracellular free Ca2+ in neuroblastoma x glioma hybrid NG108-15 cells
- ∆(9)-Tetrahydrocannabinol decreases NOP receptor density and mRNA levels in human SH-SY5Y cells
- Agonist selective modulation of tyrosine hydroxylase expression by cannabinoid ligands in a murine neuroblastoma cell line
- Anandamide, an endogenous cannabinoid, inhibits calcium currents as a partial agonist in N18 neuroblastoma cells
- A predominant role for inhibition of the adenylate cyclase/protein kinase A pathway in ERK activation by cannabinoid receptor 1 in N1E-115 neuroblastoma cells